For the patient-derived cells, we found (by qRT-PCR) that mRNA expression of IFN-α, IL-6, IL-8, IL-12β, ISG-15, MX1, MX2, and RSAD2 was lower, while the expression of IL-1β, IL-4, IDO-1, IFN-γ, IFI44, IFI44L, MT1A, TRIB3, and TNF-α was higher in LTBI cases compared to healthy controls and active TB cases (Supplementary Figures 8A–C). This evidence concerns the gene ISG15 and tuberculosis.