In our previous studies, we showed that the mixture of ten microRNAs comprising mmu-miR-15a/b-5p, mmu-mir-26a/b-5p, mmu-mir-27b-3p, mmu-miR-29a-3p, mmu-miR-93-5p, mmu-miR-103/107-3p, mmu-miR-206-3p and mmu-miR-320-3p can counteract Dicer1 deletion-mediated hyperphagic obesity (10). This evidence concerns the gene DICER1 and obesity disorder.