Patients were diagnosed with non-functioning adenoma (NFA) (n=118; 44%), acromegaly (n=42; 16%), prolactinoma (n=39; 13%), Cushing’s disease (n=36; 13%) craniopharyngioma (n=20; 7%), RCC (n=10; 4%) FSH-adenoma (n=3; 1%) or thyrotropinoma (n=3; 1%). This evidence concerns the gene BRD2 and TSH-secreting pituitary adenoma.