Researchers found that dysregulated levels of oxidative stress indicators comprising superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), malondialdehyde (MDA), and lactate dehydrogenase (LDH) may give rise to high risks of neuronal apoptosis in rats with Alzheimer's disease [25]. Here, CAT is linked to early-onset autosomal dominant Alzheimer disease.