Their prioritized genes are listed as follows: PITX2, ZFHX3, NKX2-5, CAV1, IGF1R, KIAA1755, NEURL1, GORAB, ESR2, ZEB2, and WIPF1. Of the genes associated with these loci, PITX2, ZFHX3, and NKX2-5 were already known to be associated with CES and AF. The gene discussed is NKX2-5; the disease is atrial fibrillation.