When the diagnostic value of these key genes were evaluated between the normal skin from keloid-prone or normal individuals (GSE113619), the AUC values of COL1A1, COL1A2, COL3A1, COL5A1, and COL5A2 in keloid were 0.650, 0.625, 0.575, 0.525, and 0.450, respectively (Figure 12(e)). This evidence concerns the gene COL3A1 and keloid.