SliTrk5 has been identified as one of the factors modulating basic function of the physiological and pathological mechanism of CNS, such as neurite outgrowth, dendritic elaboration, synaptogenesis, and neuronal signal transmission, which was associated to the development of neuropsychiatric disorders, including obsessive-compulsive spectrum disorders (OCDs), attention deficit/hyperactivity disorder (ADHD), autism spectrum disorders (ASDs), and Parkinson's disease (PD) [35]. The gene discussed is SLITRK5; the disease is autism spectrum disorder.