The above mechanism can be one of the reasons for the recovery of COVID-19 cases (with or without hypertension) with the treatment of antihypertensive medications like ACE inhibitors and type 1 angiotensin receptor inhibitors because these drugs enforce to gained ACE2 expression and the ACE2-Ang1-7-Mas receptor axis, which is related with diminished expression and effects of angiotensin 2 in tissues such as the lungs and heart (28,50). This evidence concerns the gene ACE2 and hypertensive disorder.