What stands out of the results is that while StAR gene expression and, as a result, testosterone levels increased in the PCOS group comparing with the control group, they decreased in a dose‐dependent manner after hypothyroidism, with this increase being significant in the PCOS group compared with the control group, and those decreases were also significant in the groups that received 2 and 4 mg/kg of PTU compared with the PCOS group. The gene discussed is STAR; the disease is hypothyroidism.