IRF4 and prostate neoplasm: Furthermore, we found that eight of the suggested genes (NFIB, FBXW7, PPARA, ETV4, NCOA2, CYP7B1, OPCML, IRF4) have been demonstrated to be involved in neoplastic processes (Supplementary Fig. 1 A) and four of them, the ETV4, NCOA2, CYP7B1 and PPARA genes, have been shown to be associated with malignant neoplasms of the prostate (Supplementary Fig. 1B and Supplementary Table 1).