Furthermore, we found that eight of the suggested genes (NFIB, FBXW7, PPARA, ETV4, NCOA2, CYP7B1, OPCML, IRF4) have been demonstrated to be involved in neoplastic processes (Supplementary Fig. 1 A) and four of them, the ETV4, NCOA2, CYP7B1 and PPARA genes, have been shown to be associated with malignant neoplasms of the prostate (Supplementary Fig. 1B and Supplementary Table 1). This evidence concerns the gene IRF4 and prostate carcinoma.