In the multivariate analysis, the following variables were confirmed to be independent risk factors for AL: Tumor location (p < 0.001), Age (p = 0.012), Sex (p = 0.041), Hemoglobin (p = 0.001), C-reactive protein (p = 0.040), LCR (p = 0.003) and NRS2002 (p = 0.006), (Table 2). The gene discussed is CRP; the disease is neoplasm.