KRT5 and pemphigus: Similar to the epidermal changes in Chrm3−/− mice, anti-CHRM3 pemphigus autoantibodies upregulate K5 and downregulate K10 (Chernyavsky et al., 2022) in mice—findings that are mirrored in the epidermis of patients with pemphigus vulgaris (Williamson et al., 2006).