By contrast, some more recent research demonstrated that IL-8 promoted epithelial to mesenchymal transition (EMT) by increasing the MMP-2, MMP-9 and EpCAM expression, and stimulated the anchorage-independent growth, proliferation, angiogenic potential, adhesion and invasion in ovarian cancer cells [45–47]. The gene discussed is CXCL8; the disease is ovarian carcinoma.