Some factors such as shortness of breath, nausea or vomiting, chest distress, inappetence, comorbidities such as hypertension, diabetes, and cancer, white blood cell count >10.0 × 109/L, CRP level ≥10 mg/L, LDH level ≥250 U/L, AST level >40 U/L, ESR, sodium level, and CD4+ T cell counts were not significant factors in the multivariate regression analysis. This evidence concerns the gene ESR1 and cancer.