ESR1 and breast carcinoma: In our study, no significant correlation was found between pathological type, histological grade, percentage of tumor stroma infiltrating lymphocyte, lymph-vascular invasion, estrogen receptor, progesterone receptor, human epidermal growth factor 2, Ki67, molecular subtypes, and NSLN metastasis, which is different from relevant literature reports.[26–30] The purpose of this study is to provide an important reference value for surgeons considering whether SLN positive breast cancer patients can omit ALND or not.