7 Laws Laws S S Hone Hone E E Gandy Gandy S S Martins Martins R. R. Expanding the association between the APOE gene and the risk of Alzheimer’s disease: Possible roles for APOE promoter polymorphisms and alterations in APOE transcription Expanding the association between the APOE gene and the risk of Alzheimer’s disease: Possible roles for APOE promoter polymorphisms and alterations in APOE transcription J Neurochem J Neurochem 2003 2003 84 84 1215 1215 1236 1236 10.1046/j.1471-4159.2003.01615.x 10.1046/j.1471-4159.2003.01615.x 12614323 12614323. The gene discussed is APOE; the disease is Alzheimer disease.