Levels of TFRC (P<0.001), PHKG2 (P=0.008), FADS2 (P=0.023), and NOX1 (P=0.049) mRNA relative expression were higher in tumor tissues than in control tissues (Figure 11A–D); however, levels of ALOX5 (P<0.001) mRNA relative expression were reduced in cancerous tissues compared with control tissues (Figure 11E), which were consistent with the bioinformatic results. The gene discussed is ALOX5; the disease is neoplasm.