PRKCD and Anxiety: Since CeAL PKCδ neurons regulate CeAM outputs and the expression of anxiety-like behaviors, and since acute and chronic alcohol has been shown to affect anxiety-like behaviors (Silberman and Winder, 2015; Walker, 2021), it is possible that PKCδ may play a role in alcohol induced changes in GABAergic and glutamatergic transmission in the CeA that drive continued alcohol intake in AUD, although this has not been directly tested.