CCR2‐deficient mice exhibited increased bone mass with decreased numbers of osteoclasts.(74) Although the role of CCR2 in osteoporosis‐induced bone loss is controversial,(74, 75) the MCP‐1/CCR2 axis has also been shown to provide crucial signaling for recruitment of mesenchymal progenitor cells to fracture sites and CCR2 deficiency delayed fracture healing.(76) Our findings suggest that bone mass inside the bone tunnel was increased in CCR2‐deficient mice compared to control mice. Here, CCL2 is linked to osteoporosis.