SLC7A11 and neoplasm: A recent study showed that IFN-γ released by CD8+ T cells downregulated the expression of SLC3A2 and SLC7A11, the two subunits of the glutamate–cysteine antiporter system x−, and inhibited cystine uptake, thus inhibiting GPX4 synthesis, promoting lipid peroxidation, and ultimately inducing ferroptosis in tumor cells [49].