SIGLEC1 and infection: CD169 exhibits important phagocytic functions, including facilitating antigen uptake, and is highly expressed on myeloid cells in draining lymph nodes following infections (Crocker et al., 1997) and was recently shown to be a prognostic factor in malignant melanoma and as a biomarker of SARS-CoV-2 infection (Saito et al., 2015; Bedin et al., 2021).