Our group observed that PITX2, PNCK, GLIS1, SCNN1G, MMP1, ZNF488, and SHISA9 were significantly correlated with several immune cells, suggesting that the presence of these genes helps to ease the entry of immune cells into HCC, which can help prevent the disease (Figure 5). The gene discussed is PNCK; the disease is hepatocellular carcinoma.