VEGFA and cavernous hemangioma: Major features used to discriminate cavernous hemangiomas from capillary hemangiomas include the observation of “normal” vascular endothelial cells in cavernous hemangiomas and the over-expression of vascular endothelial growth factor A (VEGFA) and fibroblast growth factor receptor 1 (FGFR1) in capillary hemangiomas during the proliferative stage (Tan et al., 2000).