IL-17 hampers dexamethasone’s inhibitory effect on IL-6 expression in PBMCs by increasing GR-β (48), and budesonide’s suppressive effect on IL-8 production in airway epithelium 16HBE cells through reduction of HDAC2 activity (49). We also observed a positive correlation between IL-17 and GR-β/GR-α in ILD specimens, and a reduction of GRβ and HDAC2 in IL-17-treated fibroblasts. Here, HDAC2 is linked to interstitial lung disease.