CD4 and cancer: Moreover, by multiple stepwise regression analysis, the amounts of comorbidities were the risk factor for lymphocyte percentages, CD3+CD4+ percentage, CD3+CD8+ percentage, nonalcoholic fatty liver disease was the risk factor for lymphocyte counts and CD3+ counts, cardiovascular disease was the risk factor for CD3+CD4+ percentage and CD3+CD8+ percentage, diabetes mellitus was the risk factor for CD3+CD8+ percentage, and cancer was the risk factor forCD3+ percentage (Table 5).