The function of circRNAs as TSGs has also been proven in many cancers, including circDDX17 (102), circ_PLXNB1 (103), circTADA2A (104), and Circ-SMARCA5 (105) in colorectal cancer, circ_0004872 (106), circDIDO1 (107), circMAPK1 (108), circ_0035445 (109) and circCCDC9 (110) in gastric cancer, circPLEKHM3 (111) in ovarian cancer, circ-MYBL2 (112) in multiple melanoma, and circSLC8A1 (113) in prostate cancer. This evidence concerns the gene SMARCA5 and Familial prostate cancer.