For HF hospitalization, the continuous NRI after the addition of resting cardiac power/mass in the model with established risk factors and NT-proBNP was 6.0% (95%CI: 4.7–15.2%, P = 0.026), and the IDI was 1.7% (95%CI: 1.2–4.3%, P = 0.007). This evidence concerns the gene NPPB and hydrops fetalis.