After 14 days of insulin treatment, his blood glucose concentration returned to normal, so he continued to take 7.8 mg/m2/day (divided into two equal doses) rapamycin orally on June 10 (the 16th day after rapamycin withdrawal), together with continuous subcutaneous insulin infusion (0.5 IU/h) to prevent hyperglycemia. This evidence concerns the gene INS and Hyperglycemia.