DNMT1 and glioblastoma: As demonstrated in Supplementary Figure 3C, HAUS1 expression was positively and strongly associated with the four DNA methyltransferases (DNMT1: R = 0.73, P = 1.7e − 87; DNMT2: R = 0.43, P = 8.3e − 25; DNMT3A: R = 0.56, P = 3.3e − 45; DNMT3B: R = 0.67, P = 5e − 68) in LGG samples, whereas, it was positively correlated with only DNMT2 (R = 0.22, P = 0.014) in GBM samples.