The upregulation of endoplasmic reticulum stress in endometriotic cells by its activator can remarkably inhibit NF-κB-induced inflammation by upregulating the NF-κB-negative regulators A20 and C/EBPβ, indicating the potential anti-NF-κB value of endoplasmic reticulum stress in endometriosis 49. The gene discussed is NFKB1; the disease is endometriosis.