Interestingly, Luo et al. performed the weighted gene co-expression network analysis to identify the key modules and hub genes in bladder cancer, and they found that three hub genes (DACT3, TNS1, and MSRB3) were related to lymph node metastasis and prognostic of bladder cancer, which might provide new insights into the therapeutic target of bladder cancer 58. Here, DACT3 is linked to urinary bladder cancer.