DUSP4 and cancer: DUSP4 was found to be involved in cytokine-cytokine receptor interaction, regulation of actin cytoskeleton and other pathways associated with cancer progression (Figure 5A) by KEGG pathway analysis, while the GSEA enrichment analysis showed that DUSP4 was enriched in drug metabolism, peroxisome, regulation of actin cytoskeleton and cell adhesion molecules (Figure 5B and C).