SNHG17 and pachyonychia congenita: As shown in Figures 4(c) and 4(d), GSEA suggested that SNHG17 was positively correlated with RNA metabolism, cellular response to external stimuli, DNA damage response, and cell cycle and negatively correlated with pathways in cancer and PI3K/AKT signaling in cancer, indicating that SNHG17 may not affect the progression of PC through canonical cancer-related signaling pathways.