Of these cancer driver genes, 79 were uniquely identified in the UCKT cohort, and 17 of them (BTK, CARD11, ELL, FNBP1, GNAQ, HOXD13, IKZF1, MAX, MLLT10, NTRK3, PAX5, SEPTIN6, SEPTIN9, SH3GL1, SLC34A2, TAL1, and TRAF7) exhibited mutations that occurred in two or more patients (Table 3). The gene discussed is BTK; the disease is cancer.