Perhaps, we should also advise the lean PCOS women to make regular liver function checking and modify their lifestyles, such as making exercise, changing eating habits as early as possible to prevent the progression of liver disease; simultaneously, some researches were published on the reverse of the ALT level; for instance, Javed et al. [39] reported an improvement on the marker of liver injury and fibrosis through vitamin D supplementation in overweight and obese PCOS. The gene discussed is GPT; the disease is polycystic ovary syndrome.