2021), which implies that the Sfpi1 deletion is an important mutation that largely determines the shape of the dose-response curve (i.e., Fig. 2b explains Fig. 4). Therefore, the effect of the HRS\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$^+_1$$\end{document}1+ assumption on the rAML incidence was found to be approximately identical to the effect of HRS on cell survival and the induction of pre-leukemic cells. This evidence concerns the gene SPI1 and kidney angiomyolipoma.