DNMT1 and ovarian cancer: While the expression of NOG, S1PR1, BTG4, and CREB5 genes was significantly increased, that of RASSF9, DNMT1, BST2, and SETD1A genes was significantly decreased in CFP1-deleted A2780 and ES-2 ovarian cancer cells, based on qRT-PCR results (Fig. 5G and Supplementary Fig. S4A).