CACNA1A and pulmonary fibrosis: In the present study, MHP1-AcN decreased TβRI and TβRII expression in fibroblasts, but in bleomycin-induced lung fibrosis model, MHP1-AcN treatment inhibited the increase in Tgfbr2 without significant change in Tgfbr1 on day 14 after bleomycin exposure.