SerpinB7 knockdown in HaCaT cells drastically increased the expression of psoriasis-related chemokines (CCL20, CCL27, CXCL1, CXCL2) and antimicrobial peptides LL37 and S100A8 in the M5-stimulated in vitro psoriatic model (Supplementary Fig. 5C). The gene discussed is CXCL1; the disease is psoriasis.