We observed a similar trend toward reduced NCOR1 expression and increased RARA and overall reduced NCOR1/RARA expression ratio upon analysis of a second study using human iPSC-derived retinal organoids from RP patients bearing instead RP2 mutations, that account for ~5% of all cases of X-linked RP25 (Fig. 8h). Here, NCOR1 is linked to retinitis pigmentosa 1.