To further elucidate the differences in response to kinase inhibitors between FLCNPOS and FLCNNEG RPTEC and UOK257 cells, we performed comprehensive phosphoproteomic profiling of the UOK257 (FLCNNEG) and the isogenic FLCN reconstituted tumor cell line UOK257-2 (FLCNPOS). Here, FLCN is linked to neoplasm.