vWe analyzed the clinical characteristics related to the microbial diversity and composition of tumor tissues, including gender, age, body mass index (BMI), smoking status, tumor purity, stage, tumor mutational burden (TMB) index, molecular functional portrait (MFP) signature, and immune characteristics defined by immune subtype, IPS score (defined as the number of tumor-associated immune cells with positive ctla4 staining/total number of tumor-associated immune cells), lymph node status, B-cell receptor (BCR) diversity, and T-cell receptor (TCR) diversity. Here, CTLA4 is linked to neoplasm.