In more detail, markers of atherosclerosis, cardiovascular disease (CVD), and inflammation include circulating compounds such as C-reactive protein (CRP), fibrinogen, immunoglobulins, adhesion molecules, and pro-inflammatory cytokines (e.g., macrophage migration inhibitory factor (MIF)), and most of them are dysregulated in depressed patients [9, 10]. This evidence concerns the gene MIF and cardiovascular disorder.