In 2014, Xu et al. reported that 2,601 health-check examinees with fatty liver on ultrasound showed a higher median serum AFP level (3.10 ng/mL) than the no fatty liver group (n = 7,199, 2.90 ng/mL), but AFP level was not an independent factor for fatty liver in the multivariable analysis [13]. This evidence concerns the gene AFP and Hepatic steatosis.