If PCSK9 SNP rs662145 C > T predisposes individuals to psoriasis by increasing their baseline cutaneous expression of IL-36, one would expect that keratinocytes homozygosity for the PCSK9 reference allele should have low IL36 expression, as individuals homozygous for the PCSK9 reference allele are not predisposed to psoriasis. Here, PCSK9 is linked to psoriasis.