GATA3 and asthma: However, in vitro gene expression studies using tissues from patients with asthma and ASD have found gene polymorphisms close to the identified loci observed in the previous study (i.e. cyclooxygenase‐2 (COX‐2), adrenoceptor beta 2 (ADBR2) and GATA‐binding protein 3 (GATA3)) which are involved in inflammation and immune regulation.