Several signaling pathways, such as the PI3K/AKT/NF-κB signaling pathway, PTEN/PI3K/AKT signaling pathway, Wnt/beta-catenin pathway, and Sonic Hedgehog signaling pathway, are closely related to the occurrence, development, and drug resistance of cancers ([17]; H. [18–21]). Here, NFKB1 is linked to cancer.