CD40LG and interstitial lung disease: Patients with SSc-ILD have decreased numbers of B cells that secrete IL-10 (B10 cells) when stimulated via a short activation protocol (with the oligodeoxynucleotide CpG for 5 h), but not when activated via a long stimulation protocol (with CpG and CD40L for 48 h), suggesting thereby that B10 cells and not their precursors may be also implicated in the ILD pathogenesis.