However, some indicators were persistently lower in critical patients than in their non-critical counterparts, and these indicators were indicative of immune damage (lymphocytes and eosinophils), coagulation disorder (platelets), impaired liver function (A/G), and malnutrition (hemoglobin, RBCs, TP, prealbumin, and albumin). The gene discussed is TTR; the disease is nutritional deficiency disease.