Our results also demonstrate that DIO-induced increases in serum triacylglycerol concentration are not always coupled with a downregulation of serum adiponectin concentration, given that the hypertriglyceridemia in dietary groups OB1 and OB2 occurred against the background of both elevated serum adiponectin (OB1 vs. CON) or unchanged adiponectin levels (OB2 vs. CON). This evidence concerns the gene ADIPOQ and hypertriglyceridemia.